Answer:The crystal structures of five 6-mercaptopurine derivatives, viz. 2-[(9-acetyl-9H-purin-6-yl)sulfanyl]-1-(3-methoxyphenyl)ethan-1-one (1), C16H14N4O3S, 2-[(9-acetyl-9H-purin-6-yl)sulfanyl]-1-(4-methoxyphenyl)ethan-1-one (2), C16H14N4O3S, 2-[(9-acetyl-9H-purin-6-yl)sulfanyl]-1-(4-chlorophenyl)ethan-1-one (3), C15H11ClN4O2S, 2-[(9-acetyl-9H-purin-6-yl)sulfanyl]-1-(4-bromophenyl)ethan-1-one (4), C15H11BrN4O2S, and 1-(3-methoxyphenyl)-2-[(9H-purin-6-yl)sulfanyl]ethan-1-one (5), C14H12N4O2S. Compounds (2), (3) and (4) are isomorphous and accordingly their molecular and supramolecular structures are similar. An analysis of the dihedral angles between the purine and exocyclic phenyl rings show that the molecules of (1) and (5) are essentially planar but that in the case of the three isomorphous compounds (2), (3) and (4), these rings are twisted by a dihedral angle of approximately 38°. With the exception of (1) all molecules are linked by weak C—H⋯O hydrogen bonds in their crystals. There is π–π stacking in all compounds. A Cambridge Structural Database search revealed the existence of 11 deposited compounds containing the 1-phenyl-2-sulfanylethanone scaffold; of these, only eight have a cyclic ring as substituent, the majority of these being heterocycles.
Keywords: crystal structure, mercaptopurines, supramolecular structure
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Chemical context
Purines, purine nucleosides and their analogs, are nitrogen-containing heterocycles ubiquitous in nature and present in biological systems like man, plants and marine organisms (Legraverend, 2008 ▸). These types of heterocycles take part of the core structure of guanine and adenine in nucleic acids (DNA and RNA) being involved in diverse in vivo catabolic and anabolic metabolic pathways.
6-Mercaptopurine is a water insoluble purine analogue, which attracted attention due to its antitumor and immunosuppressive properties. The drug is used, among others, in the treatment of rheumathologic disorders, cancer and prevent
Step-by-step explanation:
Answer:261
Step-by-step explanation:
How many sides do 4 nonagons and 4 triangles have in all?
Answer: Regular nonagon has 9 sides. 9×9×9×9 is 6,561 which is the total of 4 nonagons. A regular triangle has 3 sides. 3×3×3×3 is 81 which is the total of 4 triangles. When you add 6,561 and 81 together, it's 6,642. Therefore, 6,642 is the 4 nonagons and 4 triangles in total.
What is the radius of a cylinder if it has a volume of 769.3 cubic meters and a height of 5 meters? (Use 3.14 for π.) 49 m 14 m 7 m 21 m
Answer:
7m
Step-by-step explanation:
v=πr^2h
769.3=3.14*r^2*5
769.3=15.7r^2
769.3/15.7=15.7r^2/15.7
49=r^2
√49=√r^2
√49=r
r=7m
4/7 divide by 3/8 = 7/4 * 3/8 = 21/32
what did Alex do wrong? ASAP
Answer:
Step-by-step explanation:
He should’ve flipped 3/8 to 8/3.
= 7/4 x 8/3 = 56/12
Answer:
He should have done 4/7 * 8/3 = 32/21
Step-by-step explanation:
4/7 divide by 3/8 = 7/4 * 3/8 = 21/32
To divide 4/7 by 3/8, keep 4/7 and multiply by the reciprocal of 3/8, so do the multiplication below:
4/7 * 8/3
His mistake is using the reciprocal of the first fraction instead of the reciprocal of the second fraction.
what are the rules for multiplying negative integers
Answer:
Negative time a negative equals a positive!
Step-by-step explanation:
When you multiply two negative numbers or two positive numbers then the product is always positive. The same also goes for dividing negative integers.
There are 5 girls in a class of 14 students what is the ratio of boys ?
HELP ASAPP
LEASE NEED THE ANSWER NOW Pleasee
Answer:
9:14
Step-by-step explanation:
If the ratio of girls to students is 5:14, that means there are 9 boys for every 5 girls. Therefore, the ratio of boys to students is 9:14.
Answer:
9
Step-by-step explanation:
Girls = 5 out of 14
So, ratio of girls to total strength is 5:14
Boys = 14-5 = 9 boys
So, ratio of boys to total strength is 9:14
Ratio of boys is 9
Hope it helped. Pls mark me the BRAINLIEST!
Solve these equations.
|x-3|= 4
Answer:
x = 7 or x = -1
Step-by-step explanation:
Remove the absolute value.
x - 3 = 4 or x - 3 = -4
Solve.
x - 3 = 4
x = 7
x - 3 = -4
x = -1
What is the relationship between x and y?
Oy and x stay constant
Oy increases as x increases
Oy decreases as x increases
Oy stays constant as x increases
At Whitney's Hats, 60% of the 100 hats are baseball caps. How many baseball caps are there?
Answer:
60
Step-by-step explanation:
60% of 100 is 60
100 = 100%
60 = 60%
Answer:
The answer is 60
Step-by-step explanation:
The answer is 60 because
\(0.6 * 100 = 60\)
I don’t get it, what am I supposed to be multiplying!?!
Answer: 5400
Step-by-step explanation: image attached
Answer:
5400
Step-by-step explanation:
we need to calculate the area of big box (prism).
volume = 4 1/2 X 5 X 3 3/4
= 84.375 in³.
volume of small cube = 1/4 X 1/4 X 1/4
= 0.015625 in³.
now we need to find how many of the small ones go into the big one.
84.375/0.015625
= 5400.
Find the mean of the data in the bar chart below.
puppets
Puppets made by each puppeteer
5
Number of puppets
0
Alex
Kalin
Bruce
Davi
Puppeteer
Just look at the picture
Answer:
2.5
Step-by-step explanation:
the mean, better known as the average, can be found by finding the sum of all numerical data and dividing by the amount of your data. so 1+4+3+2=10 and 10 divided by 4=2.5
Answer:
2.5
Step-by-step explanation:
PLSSS HELP ME, WILL MARK BRAINLIEST!!!
Answer: 8x³y²(2-3xy²)
Step-by-step explanation:
16x^3y^2 + -24x^4y^4
Factor out GCF: 8x^3y^2
Your teacher created a 2 g/L salt-water solution (solution A) and a 2.5 g/L salt-water solution (solution B), both in 500 mL of water. Using the concentration equation, which solution is more concentrated? How do you know?
Answer:
Solution A
Step-by-step explanation:
John says the transformation rule (x, y) Right-arrow (x + 4, y + 7) can be used to describe the slide of the pre-image (4, 5) to the image (0, –2). What was his error?
points :)
Answer:
His error was that he used the wrong transformations. The transformations should have been 4 left and 7 down. Instead, John used the transformations of 4 right and 7 up. I hope this helps!
Step-by-step explanation:
the ratio of the number of oranges to apples to bananas is 8:5:2. if there are 120 fruits in total, how many bananas are there
Answer:
Step-by-step explanation:
To find the number of bananas, we need to determine the proportion of bananas in the total number of fruits based on the given ratio.
Let's assume that the ratio of oranges, apples, and bananas can be represented by 8x, 5x, and 2x, respectively, where x is a common multiplier.
The sum of the parts in the ratio is 8x + 5x + 2x = 15x.
We know that the total number of fruits is 120. Therefore, we can set up the following equation:
15x = 120
To solve for x, we divide both sides of the equation by 15:
x = 120 / 15
x = 8
Now that we know the value of x, we can find the number of bananas by multiplying it by the corresponding part of the ratio:
Number of bananas = 2x = 2 * 8 = 16
So, there are 16 bananas in total.
We can add all the parts to the ratio and get 15. Out of 15 parts, 2 are bananas. Now we can calculate how many fruits are in one part. One fifteenth of 120 is 8, so there are 8 fruits in one part. 2 parts are bananas, so multiplying 8 with 2 gives us our answer, 16.
I know this question is not about math or science but my friends are saying the Leonardo DiCaprio when he was young is hotter than Zac Efron now and when he was young. I need y’alls opinions.
Who is hotter, young Leonardo DiCaprio or 35 year old Zac Efron? My pick is Zac Efron but I want some opinions.
Answer:
it's Zac Efron for sure, Leonardo DiCaprio is just not the same...
I will give you branley for this if you get it correct: A hot chocolate recipe calls for three teaspoons of cocoa for every cup of milk. How many teaspoons of cocoa are needed for a batch that uses three cups of milk?
Answer:
9 teaspoons
Step-by-step explanation:
I posted a Picture thingy Down There, read it
approximate the square root to the nearest integer
-√18
Answer:
-4
Step-by-step explanation:
4² is 16, 5² is 25, and 18 is closest to 16. The nearest integer would be 4, or rather -4 in this case.
PLS HELP I WILL MARK BRAINLIEST!
I need some help for this and the graph won’t let you use decimals as the answer. Tip: 1/3 = 0.3
.
Answer:
\(\large\begin{array}{|c|c|}\cline{1-2}x&y\\\cline{1-2}6&2\\\cline{1-2}12&4\\\cline{1-2}18&6\\\cline{1-2}\end{array}\)
See attachment for the graph of the equation.
Step-by-step explanation:
Given equation:
\(y=\dfrac{1}{3}x\)
To complete the table, find the corresponding values of y by substituting each given value of x into the equation.
\(x=6 \implies y=\dfrac{1}{3}(6)=\dfrac{6}{3}=2\)
\(x=12 \implies y=\dfrac{1}{3}(12)=\dfrac{12}{3}=4\)
\(x=18 \implies y=\dfrac{1}{3}(18)=\dfrac{18}{3}=6\)
Therefore the completed table is:
\(\large\begin{array}{|c|c|}\cline{1-2}x&y\\\cline{1-2}6&2\\\cline{1-2}12&4\\\cline{1-2}18&6\\\cline{1-2}\end{array}\)
To graph the equation, plot the ordered pairs on the given coordinate plane:
(6, 2)(12, 4)(18, 6)Draw a straight line through the points. (See attachment).
Mackey invested some money in an account paying 6% interest for one year. She invested $1000 more than this amount in an account paying 8.5%. How much did she invest in total if the total interest earned in the year was $737.50?
Step-by-step explanation:
Let's assume the amount Mackey initially invested in the 6% account is x dollars.
According to the given information, Mackey invested $1000 more than x in the 8.5% account, which means she invested (x + $1000) dollars in that account.
The total interest earned from the 6% account would be 0.06x dollars, and the total interest earned from the 8.5% account would be 0.085(x + $1000) dollars.
The total interest earned in the year is given as $737.50, so we can set up the equation:
0.06x + 0.085(x + $1000) = $737.50
Simplifying the equation:
0.06x + 0.085x + 0.085($1000) = $737.50
Combining like terms:
0.145x + $85 = $737.50
Subtracting $85 from both sides:
0.145x = $737.50 - $85
0.145x = $652.50
Dividing both sides by 0.145:
x = $652.50 / 0.145
x ≈ $4500
Therefore, Mackey initially invested approximately $4500 in the 6% account, and she invested $1000 more, which means she invested a total of $5500.
$4500
$4500
$4500
$4500
EASY FOR PEOPLE THAT KNOW HOW TO DO MATH, HELP NEEDED
Answer:
1 and 5/24 gallon left
Step-by-step explanation:
https://www.slader.com/discussion/question/mark-wants-to-paint-a-mural-he-has-113-gallons-of-yellow-paint-114-gallons-of-green-paint-and-78-g-2/
its a reliable link
Find the surface area of a top open cylinder
12 in radius
2 in height
The surface area of the top open cylinder is 6810.149 sq.cm.
A cylinder is a three-dimensional solid that consists of two congruent surfaces (bases) and one lateral surface.
Surface area of a cylinder = Base area + Lateral area
Base area of a cylinder = 2 × π × r²
Lateral area of a cylinder = (2 × π × r) × h
Therefore, here base area of a cylinder = 2× π × 12²
= 5837.27 sq.cm.
And, lateral area of a cylinder = (2 × π × 12) × 2
= 972.8784 sq.cm.
Therefore, total surface area of a cylinder = 5837.27 + 972.8784
= 6810.149 sq.cm.
To know more about surface area:
https://brainly.com/question/951562
NEED HELP ASAP 27 hundredths is written this way: 0.27. Which scale shows 0.27 kilogram?
Robin wants to buy a membership at a carwash this summer so that she can keep her car clean. She compared deals from Speedy Clean Carwash and Sudsy Bubbles Carwash to decide which membership to get. Robin arranged the information in the tables below.
How many times will Robin need to wash her car to spend the same amount at both carwashes?
P.S.: I attached the table below:)
Help me!!!!!!! I will give brainliest for first one with correct answer.
Answer: The answer is
YesNoNoYesYesYesStep-by-step explanation:
I am pretty sure this is correct:)
Answer:
yes
no
yes
yes
no
yes
yes
Step-by-step explanation:
the larger of two numbers is five more than three times the smaller number. their sum is 33 . find larger numbers.
write the equation and find the larger number
Answer: It will be in the explanation
Step-by-step explanation:
"five more than three times the smaller number" will mean:
x = 3y + 5 [equation 1]
x + y = 33 [equation 2]
Rearrange the first equation like this :
x - 3y = 5
x + y = 33
Doing this puts the variables on the same side. Now we gotta find the value of x. In order to do so, we have to use both of the equations provided to solve and make it one equation with x and not y.
y = 33 - x
x = 5 + 3(33 - x)
Use the distributive property for 3(33 - x), which will be:
x = 5 + 99 - 3x
Further solving it:
4x = 104 [divide this by 4 to get x by itself]
Final answer is
x = 26
Hope this helps :D
A project will take a total of 720 person-days to complete. If the project must be completed in 30 days, how many people must be employed? PLEASE HURRY
Answer:
192 hours per day / 8 hours per person per day = 24 people
Step-by-step explanation:
Assuming each person works for 8 hours a day, the total number of hours needed to complete the project is:
720 person-days x 8 hours = 5,760 hours
To complete the project in 30 days, the total number of hours needed per day is:
5,760 hours / 30 days = 192 hours per day
would it be chemical weathering or mechanical weathering
Answer:
Mechanical/physical weathering - physical disintegration of a rock into smaller fragments, each with the same properties as the original. Occurs mainly by temperature and pressure changes
Chemical weathering - process by which the internal structure of a mineral is altered by the addition or removal of elements.
Step-by-step explanation:
I REALLY NEED BRAINIEST THX
help meeeeeeeeee plz qwq
Answer:
1. A
2. C
3. B
4. D
5. The customer will save $5 by purchasing the annual subscription
6. The best option for savings would be the 30% off option
8. A) True B) False C) False
Step-by-step explanation:
This is all I could answer, I'm not sure how to answer 7 or 8 for B and C
But I hope this helps you get started.
HELP HELP HELP ME PLEASE !! GIVING BRAINLIEST
Eva wants to make 2 pieces of pottery. She needs 3/5 -pounds of clay for one piece and 7/10 -pounds of clay for the other piece. She has three bags of clay that weigh 4/5 pound each. How many bags of clay will Eva need to make both pottery pieces? How many pounds of clay will she have left over?
Answer:
she would have 3.375 full bags left over and 2.7lbs left over
Step-by-step explanation:
you convert 4/5 to .8 and multiply by 5 to get the total weight,4. you convert the amount needed 3/5 and 7/10 to .6 and .7. Add together to get 1.3. Do 4 minus 1.3. you get 2.7lbs left over. You divide 2.7 by .8, the amount in the bags to get 3.375 bags left over
Answer:
Pretty sure it is 1 and 1/10
first I added 3/5 and 7/10 to find the total clay she used.
she used 1 and 3/4lbs of clay for both pieces of pottery witch is 1.3.
She has 3 bags of clay that weigh 4/5 pound each so I multiplied 4/5 by 3 to get 2 and 2/5 witch is 2.4.
Since she was 2.4 lbs total and she used 1.3lbs I subtracted 1.3 from 2.4 to get 1.1.
Last I converted 1.1 to 1 and 1/10.
I hope this helps.