Gene: HOXD13 1. Name of the gene 2. Summary of mutations or polymorphisms associated with that gene. 3. Phenotypic changes associated with the mutation(s) or polymorphisms 4. An explanation that provides a link between the mutation, protein function, and phenotypic variability

Answers

Answer 1

Below the answers of Gene :

1. The name of the gene is HOXD13.

2. A variety of genetic mutations have been identified in HOXD13 that are linked to polydactyly, a limb malformation disease characterized by extra fingers and/or toes. There are three known mutations that can cause polydactyly when they occur in HOXD13, including c.776A>C, c.782C>T, and c.901G>A.

3. Polydactyly is a condition that is characterized by the development of extra fingers or toes. The presence of an extra finger or toe is a common phenotypic feature associated with HOXD13 mutations. Additionally, there may be other limb malformations such as underdeveloped bones and incomplete separation of digits.

4. HOXD13 is a transcription factor that is involved in the development of the limbs. The protein functions by regulating gene expression during limb development.

Mutations in HOXD13 can disrupt the normal function of the protein, leading to the development of extra fingers or toes. The severity of the phenotypic changes is likely to be influenced by the specific mutation and the extent to which it disrupts the protein's function.

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Related Questions

Subclavian vein
Which vessel does the tip of a central venous catheter terminate in?

Answers

The tip of a central venous catheter terminates in the superior vena cava.

A central venous catheter (CVC) is a long, thin, flexible tube that is inserted into a vein, usually in the neck, chest, or groin. It is used to give medication, fluids, or nutrition to a patient or to draw blood for laboratory testing.

The superior vena cava is a large vein that carries blood from the upper body, including the head, arms, and chest, back to the heart. The tip of the CVC is positioned in the superior vena cava so that the medications, fluids, or nutrition can be administered directly into the bloodstream, where they can quickly reach the heart and the rest of the body.

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Which animal is native to a different part of the world than the other two? walrus polar bear penguin.

Answers

Penguin is an animal that is native to a different part of the world other than the other two

What is native species?

Native species refers to species of organisms that of a particular origin. They are organism found in a location where they are native to or have there origin there .

Therefore, Penguin is an animal that is native to a different part of the world other than the other two

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the endocrine system is composed of various glands that secrete hormones. by what mechanism do they function?

Answers

The endocrine system is composed of various glands that secrete hormones. These glands function through a mechanism called hormone secretion. Here's a step-by-step explanation of the process:

1. Glands in the endocrine system produce and store hormones.
2. When the body requires a specific hormone, the gland responsible for producing it receives a signal from the brain or other regulatory systems.
3. In response to the signal, the gland releases the hormone into the bloodstream.
4. The hormone then travels through the bloodstream to its target cells or organs.
5. Once it reaches the target cells, the hormone binds to specific receptors on the cell surface or inside the cell.
6. This binding triggers a series of reactions within the cell, leading to a change in the cell's function or activity.
7. The resulting change in cellular activity helps the body maintain balance and regulate various processes, such as growth, metabolism, and reproduction.

In summary, the endocrine system functions by producing and secreting hormones from glands in response to signals from the body, allowing these hormones to regulate various processes within the target cells.

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Why cells are considered to be an essential part of understanding the origin of life?

Answers

Answer:

Cell is our microscopic structure. We have Trillions of cells in our body, which plays very important roll. Our every tissue, organ, organ system, our whole body has composed of cells. In order to make a nice and informed decision for our health, we must need to understand our body at cellular level.

Please tell me if I'm wrong, maybe brainliest? I need it to level up

All living things are made up of cells.
No cells = No life


Which of the following describes meiosis?

A. Makes new sex cells, creates 2 daughter cells each with 23 chromosomes

B. Makes new sex cells, creates 4 daughter cells each with 23 chromosomes

C. Makes new body cells, creates 2 daughter cells each with 46 chromosomes

D. Makes new body cells, creates 4 daughter cells each with 46 chromosomes

Answers

Answer:

A should be

Explanation:

i remember all this meiosis stuff from like 8th grade

An extended object is in static equilibrium if __________.only the net torque acting on the object is zeroeither the net force acting on the object is zero or the net torque acting on the object is zeroboth the net force acting on the object is zero and the net torque acting on the object is zeroonly the net force acting on the object is zero

Answers

An extended object is in static equilibrium if only the net torque acting on the object is zero.

An extended object is in static equilibrium if both the net force acting on the object is zero and the net torque acting on the object is zero. This means that the object is not accelerating or rotating, and all forces and torques acting on it are balanced.

When only the net torque acting on the object is zero, the object may still be rotating or translating at a constant velocity due to the presence of unbalanced forces.

When only the net force acting on the object is zero, the object may still be rotating due to the presence of unbalanced torques.

For an object to be in static equilibrium, all forces acting on it must be balanced, meaning that the vector sum of all forces is zero.

Additionally, all torques acting on the object must be balanced, meaning that the vector sum of all torques is zero.

This ensures that the object is not moving and is in a state of static equilibrium. Thus, the correct statement is only the net torque acting on the object is zero.

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Did the results of the cross match your prediction? If not, why do you think that was the case?

Answers

They did not match original prediction, they did not match because the firstborn offspring do not typically match their parents.

The mineral magnetite is generally black or dark gray, with a metallic luster.
Which sample is most likely magnetite?

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Answers

The sample which is most likely a magnetite is the one which is black and has metallic lustre.

What is a Magnetite?

This is an oxide of Iron which is highly magnetic and can also form a magnet under certain conditions in a magnetic field.

it has a grey-black color which is the color of the sample which should be chosen as a magnetite.

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the vertical stem, leaves, and flowers of a plant are all plant organs which are located aboveground. these organs make up the plant's _______ system.

Answers

The vertical stem, leaves, and flowers of a plant are all plant organs that are located aboveground. These organs make up the plant's shoot system.

What is the shoot system?

The shoot system, often known as the aerial system, is responsible for the plant's aboveground development, including the vertical stem, leaves, and flowers. It's distinguished from the root system, which is responsible for the plant's belowground growth and development. Both of these systems are critical for a plant's life because they allow for proper growth, nutrient and water absorption, and reproduction.

Plant organs that are aboveground, such as the stem, leaves, and flowers, form the shoot system of a plant. The shoot system is primarily responsible for the plant's aboveground development, including growth and reproduction.

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which of the following describes a phylogenetic constraint? select one: a. factors that prevent adaptive radiations in a particular phylogenetic lineage b. a convergently evolved character that is making cladistic analyses difficult c. a developmental pathway in a group of organisms that can be modified by natural selection but that is difficult to reverse d. some groups of organisms speciate less frequently than others e. high rates of extinction in a group of organisms

Answers

The correct option is : c) "a developmental pathway" in a group of organisms that can be modified by natural selection but that is difficult to reverse.

A phylogenetic constraint is a factor that limits or restricts the evolutionary options of a particular group of organisms due to their shared ancestry or evolutionary history. It can manifest in various ways, such as the inability to evolve certain traits or adaptations or the tendency to follow a particular developmental pathway. Option c is the correct answer as it describes a developmental pathway that is difficult to reverse even though it can be modified by natural selection. This means that the organisms in the group are limited in their ability to evolve new or different traits that may be advantageous in their environment.

For example, the development of wings in birds is a complex process that involves a specific set of genetic and molecular pathways. While natural selection can modify these pathways to improve flight performance, it is difficult to completely reverse the developmental pathway and evolve wings with a completely different structure. This is an example of a phylogenetic constraint that limits the evolutionary options of birds in terms of flight adaptations.

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In this experiment, potassium permanganate diffuses through the agar from an area of ______ concentration to an area of ______ concentration.

Help me fill the blanks^!!

Answers

Answer: High, Low

Explanation:

Diffusion occurs from an area of high concentration to an area of low concentration.

Which type of biomolecule contains phosphorus? A. Nucleic acid B. Protein C. Carbohydrate D. Lipid​

Answers

Answer: Nucleic Acids should be the answer.

Explanation:

Hydrogen, oxygen, nitrogen, carbon, and phosphorus combined and placed under one umbrella term, Biomolecule, are known as one thing; the Nucleic Acids.

At which location is the temperature of the ocean floor bedrock most likely highest?
1
A
2
3.
B
C
D

Answers

Seafloor bedrock is younger near the ridge and older farther away.

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Check your understanding. What did you include in your description?

supports and protects the cell

determines the shape of the cell

assists cells in communication

stores carbohydrates

allows water and smaller particles to enter the selectively permeable structure of the cell

Answers

The cell membrane is a vital component of the cell that supports and protects it, determines its shape, assists in cell communication, stores carbohydrates, and allows the entry of water and smaller particles through its selectively permeable structure.

The cell membrane, also known as the plasma membrane, plays several crucial roles in a cell's functioning.

1. Supports and protects the cell:

The cell membrane acts as a barrier between the cell's internal environment and the external surroundings, providing structural support and protecting the cell from mechanical stress or damage.

2. Determines the shape of the cell:

The cell membrane contributes to maintaining the cell's shape by providing a flexible boundary that helps define the cell's structure and prevents it from collapsing.

3. Assists cells in communication:

Cellular communication is essential for coordinating various processes within a multicellular organism. The cell membrane contains specialized proteins and receptors that enable intercellular communication by facilitating the exchange of signals and molecules between adjacent cells.

4. Stores carbohydrates:

Carbohydrates, in the form of glycoproteins or glycolipids, are present on the cell membrane's outer surface. These carbohydrates play a role in cell recognition and can serve as energy reserves for the cell.

5. Allows water and smaller particles to enter the selectively permeable structure of the cell:

The cell membrane is selectively permeable, meaning it controls the movement of substances in and out of the cell. It allows water and certain small molecules to pass through via processes such as osmosis and diffusion while regulating the entry and exit of larger molecules and ions.

In summary, the cell membrane is a dynamic structure that not only provides support and protection to the cell but also determines its shape, facilitates communication between cells, stores carbohydrates, and regulates the movement of substances in and out of the cell.

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What does the writer use to help readers understand
the sequence of steps?
What should the writer add when verbally presenting
the procedure to a group?
cup
How to Make Slime
For a fun activity, try making slime. You will need a 3-
quart mixing bowl, a tablespoon, 1/2 cup of shampoo, 1/4
of cornstarch, and 6 tbsp water.
Combine 1/2 cup shampoo and 1/4 cup
cornstarch in mixing bowl.
Add 1 tbsp water and stir.
Mix in 5 tbsp of water, one tablespoon at a time,
stirring well after each addition.

Answers

Answer: the numbered list and a demonstration

Explanation:

yethirrrr got it right

Answer:

1) A numbered list

2) A demonstration

Explanation:

What are two examples of a postzygotic barrier?

Answers

Answer:

Answer:

Explanation:

Explanation:

Answer:

hybrid inviability,hybrid sterility

Explanation:

Children living at high altitudes develop larger chest cavities by adulthood than children living at lower altitudes. This is an example of Group of answer choices environmental adaptations that occur at the individual level. acclimatization at the individual level. developmental adaptations that occur at the level of the individual during critical life stages. inheritance of increases in lung volume by high-altitude populations.

Answers

Answer:

developmental adaptations that occur at the level of the individual during critical life stages.

Explanation:

High altitudes is characterized by low amounts or concentration of oxygen. The body parts especially the lungs have to adjust and the lungs are usually expanded to allow for more oxygen for the body metabolism.

This is why Children living at high altitudes develop larger chest cavities by adulthood than children living at lower altitudes and is an example of developmental adaptations that occur at the level of the individual during critical life stages.

with the exception of [ select ] and [ select ] , most strepsirrhines are nocturnal and solitary animals.

Answers

With the exception of some lemurs and lorises, most strepsirrhines are active during the night, are nocturnal and solitary animals.

Strepsirrhines, a suborder of primates, are mostly known for their nocturnal and solitary behaviors. They are a diverse group of primates that includes lemurs, lorises, galagos, and aye-ayes. With the exception of some lemurs and lorises that are active during the day, most strepsirrhines are active during the night. This adaptation to nocturnal life is thought to have evolved as a way to avoid competition with other primates and predators.

Solitary behavior is also common among strepsirrhines, although there are some exceptions. Some species of lemurs are social and live in groups, while others are solitary. Lorises are also known to live in small family groups, but they generally hunt and forage alone.

The unique physical characteristics of strepsirrhines, such as their elongated snouts and large eyes, are adaptations that aid in their nocturnal lifestyle. Their large eyes allow them to see in low light conditions, while their elongated snouts contain specialized sensory organs that help them locate food and navigate through their environment.

In conclusion, strepsirrhines are mostly nocturnal and solitary animals, with some exceptions. Their adaptations to nocturnal life and unique physical characteristics are a testament to their evolutionary success.

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Which sphere, regarding carbon, would be most immediately affected by a decrease in sunlight?



A.Atmosphere
B.Biosphere
C.Geosphere
D.Hydrosphere

PLZ ANSWER!

Which sphere, regarding carbon, would be most immediately affected by a decrease in sunlight?A.AtmosphereB.Biosphere

Answers

Biosphere will be affected
But don’t copy in exam or u will suffer later
Mark me as brainliest

All the ecosystems on Earth are collectively referred to as the biosphere. Therefore, it comprises both live things and inanimate objects, such as sunshine and water. Thus, option B is correct.

What is the role of sunlight in biosphere?

Photosynthesis is a process that organisms like plants, algae, and cyanobacteria used to turn carbon dioxide and water into organic molecules like carbohydrates.

The primary source of organic matter in the biosphere is this mechanism.

The sun powers the biosphere. This is so because the biosphere depends on the sun for its source of energy.

The compounds known as photosynthetic pigments catch the solar energy that powers the biosphere and use it to create organic molecules out of carbon dioxide and water.

Therefore, Biosphere regarding carbon be most immediately affected by a decrease in sunlight.

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Offspring resemble their parents
because of

Answers

DNA is going to be the answer

Answer:  Each parent gives half their genetic material to their children.

Explanation:

People do not contract the tomato wilt virus. Why?
O Humans are not susceptible to viruses.
O The tomato wilt virus only affects vegetable plants.
O Specific viruses affect specific hosts.
O Humans have resistance to all viruses.

Answers

Answer:

B. The tomato wilt virus only affects vegetable plants.

Explanation:

This is because plant cell viruses lack the receptors required for entering the cell, making it impossible for them to reproduce in the body.

css 202 which of the following is (are) not a stage of an insect that has an incomplete metamorphosis life cycle?

Answers

Insects that undergo incomplete metamorphosis have three stages: egg, nymph, and adult. Therefore, the egg and nymph stages are part of an incomplete metamorphosis life cycle, and the adult stage is the final stage of development. None of these stages are not part of an incomplete metamorphosis life cycle.


In an insect with an incomplete metamorphosis life cycle, the stages typically include the egg, nymph, and adult. If a stage like pupa is mentioned in the context of CSS 202, it is not a part of an insect's incomplete metamorphosis life cycle. Incomplete metamorphosis is also known as hemimetabolous development.

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Pleiotropy and Polygenic traits are very easily confused. Please write a sentence describing the primary difference between these two inheritance patterns.

Answers

Answer:

Polygenic is a phenotype that is influenced by more than one gene, Pleiotropy occurs when one gene influences two or more unrelated phenotypic traits.

Explanation:

A polygenic trait is influenced by something, while Pleiotropy influences two or more phenotypic traits...so in simple words, one is influenced by something and the other influences different things  

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The arthropods: (Ch. 19) A. Make up more than three-fourths of all the known species of animals B. Are more widely and more densely disturbed throughout the world than members of any other phylum of animals Are segmented eucoelomate protostomes with well-developed organ systems Both A and C are correct All of the choices are correct

Answers

The arthropods : Make up more than three-fourths of all the known species of animals, are more widely and more densely disturbed throughout the world than members of any other phylum of animals, are segmented eucoelomate protostomes with well-developed organ systems. So, all of the given options are correct.

The arthropods are a diverse group of animals that belong to the phylum Arthropoda. Arthropods are known for their segmented bodies, jointed appendages, and exoskeletons. They include insects, spiders, crustaceans, and many other types of organisms. Arthropods are incredibly abundant and can be found in almost every habitat on Earth, from the deepest oceans to the highest mountains.

One of the most striking characteristics of arthropods is their incredible diversity. They make up more than three-fourths of all known animal species, and new species are still being discovered today. Arthropods have evolved to fill a wide variety of ecological niches, from herbivorous insects to carnivorous spiders, and from scavenging crustaceans to parasitic mites.

Arthropods are also incredibly successful at spreading and colonizing new environments. They are more widely and more densely distributed throughout the world than members of any other phylum of animals. This is due in part to their ability to adapt to different environments and their efficient modes of locomotion.

Arthropods are segmented eucoelomate protostomes with well-developed organ systems. Their segmented bodies allow for greater flexibility and control over movement, while their well-developed organ systems enable them to perform a wide variety of physiological functions. Overall, the arthropods are a fascinating and incredibly important group of animals that play a critical role in shaping the ecosystems of our planet.

Hence, all of the given choices are correct.

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Which of the following plant nutrients is used as an energy source? (Fuel to be oxidized for calories)?
a. Carbon Dioxide (CO2)
b. Nitrate (NO3-)
c. Potassium (K+)
d. Ammonium (NH4+)
e. None of the above

Answers

Plants obtain energy through the process of photosynthesis, in which they convert light energy into chemical energy in the form of glucose.

Here correct answer is E)

During photosynthesis, plants capture carbon dioxide (CO2) from the atmosphere and combine it with water (H2O) using sunlight and chlorophyll to produce glucose and oxygen (O2).

Nitrate (NO3-), potassium (K+), and ammonium (NH4+) are essential nutrients for plant growth and development, but they are not directly used as an energy source. Nitrate and ammonium are nitrogen sources used by plants for protein synthesis and other metabolic processes. Potassium is involved in various physiological functions in plants, such as enzyme activation and osmoregulation.

Therefore, the correct answer is option e: "None of the above" as none of the listed plant nutrients serve as an energy source directly. Energy for plants is primarily obtained through photosynthesis, utilizing light energy to convert carbon dioxide and water into glucose.

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A substance is moved ______ its concentration gradient using the energy of ______ .

Answers

A substance is moved against its concentration gradient using the energy of an electrochemical gradient.

The cell must employ energy to transfer substances against a concentration or electrochemical gradient. This energy is derived from adenosine triphosphate (ATP), which is produced during the cell's metabolism.

Pumps are active transport systems that function against electrochemical gradients. Small particles are continually passing across plasma membranes. In the face of these passive motions, active transport maintains ion and other chemical concentrations required by live cells.

These processes may use a large portion of a cell's metabolic energy supply. For example, the majority of a red blood cell's metabolic energy is utilized to maintain the cell's essential balance of external and internal sodium and potassium levels.

Because active transport systems rely on a cell's metabolism for energy, they are vulnerable to various metabolic toxins that disrupt ATP supply.

There are two ways for transporting tiny molecules and materials with low molecular weight. Primary active transport transports ions across a membrane and generates a charge differential across the membrane, which is directly dependent on ATP.

Secondary active transport is the movement of material caused by the electrochemical gradient generated by primary active transport and does not require ATP directly.

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There are a few points in the human genome where each individual differs. What is the name of those points?

Answers

Explanation:

Every human genome is different because of mutations—"mistakes" that occur occasionally in a DNA sequence. When a cell divides in two, it makes a copy of its genome, then parcels out one copy to each of the two new cells. ... These genome variations are uniquely yours.

The point at which every individual differs is called the DNA which is unique to each individual.

What is DNA?

The term DNA has to do with the genetic material that is found in the genes. It is an acronym that means deoxyribonucleic acid. It is peculiar to each individual.

Hence, the point at which every individual differs is called the DNA which is unique to each individual.

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2. In DNA, only the
varies from one nucleotide to another.
(A) phosphate
(B) base
(C) sugar
(D) amino acid

Answers

Nitrogenous bases is the correct option

Answer:base

Explanation:

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PLEASE HELP I WILL GIVE BRAINALIST AND EXTRA POINTS

Answers

Answer:

Coal-fired power plants

Explanation:

Generally speaking coal-fired power plants emit more greenhouse gas, however both emit greenhouse gases in large quantities.

can yall help me fill this in??

can yall help me fill this in??

Answers

1. 2 Hydrogen Molecules
2. Polar Molecule/ Chemical Polarity
3. Covalent Bond
4. Cohesion Property, Adhesion Property
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